About this ingredient
Ingredients
NADH (Reduced Nicotinamide Adenine Dinucleotide) is the reduced form of NAD⁺ (nicotinamide adenine dinucleotide), a coenzyme involved in cellular energy metabolism and electron transfer. NADH carries high-energy electrons that can be used in cellular energy-producing pathways, particularly mitochondrial metabolism.
NADH supplements may contain stabilized or specialized forms of reduced NADH, sometimes combined with ingredients such as CoQ10, vitamins, or other nutritional compounds. The exact NADH amount, form, stability, purity, and additional ingredients vary by manufacturer.
NADH, or reduced nicotinamide adenine dinucleotide, is the electron-rich form of NAD⁺. NAD⁺ and NADH work together as an important redox pair involved in cellular energy metabolism and the transfer of electrons during biochemical reactions. NAD-related coenzymes are required by hundreds of enzymes in the body.
In nutritional supplements, NADH is commonly positioned as an ingredient for cellular energy and mitochondrial-focused nutrition. Some products combine NADH with CoQ10, another compound involved in mitochondrial electron transport. Supplement labels can vary considerably in the amount and form of NADH used.
NADH is different from NAD⁺, NMN, and NR. NADH is the reduced form of NAD⁺, whereas NMN and nicotinamide riboside are compounds used in pathways that contribute to NAD⁺ production. Current research into NAD-related supplementation is active, but evidence for broad anti-aging or disease-prevention benefits remains inconclusive.
NADH may be available as tablets, capsules, lozenges, or combination nutritional formulas. Because reduced NADH can be sensitive to formulation and storage conditions, consumers should follow the manufacturer's storage instructions and check the exact product label.